The best founders “don’t build to spec”.
And don’t limit themselves by “what investors want”.
—
Still, YC’s “Agentic spaces to build” is a good distillation:

4. Full-stack AI Companies
Build AI-first companies to take on traditional incumbents.

13. Software Tools To Make Robots
Platforms to simplify development of robotic systems.

8. Internal Agent Builder
Tools for Co’s to build agents for internal processes/workflows

11. The Future of Education
Create outcome-based, scalable, and personalized learning experiences.

12. AI for Scientific Advancement
AI to accelerate R&D in chemistry, biology & materials science

5. AI Voice Assistants for Email
I’m waiting for an email app with just a mic-button. Nothing else.

6. AI Personal Assistant
AI assistants that organise AND execute tasks

2. Voice AI
Capability to handle voice interactions across languages, accents and nuances

14. AI Personal Tutor for Everyone
Personalized AI-driven educational tools (diff from “Future of Edu”?).

1. AI Research Labs
Use AI to advance AI research. Very meta.

10. Healthcare AI
Eliminate errors, reduce paperwork, better post-op care, analysis-rich diagnostics

9. AI Personal Finance
Personal finance management, budgeting, and more informed financial decisions

3. AI Residential Security
AI solutions for home security, smarter surveillance and threat detection.

7. More Design Founders
Leveraging designers user-centric approach and aesthetic sensibilities to create standout products

Bonus:
15. Has Y-Combinator given up on AI for CleanTech & Sustainability?

How I’d prioritise:
Civilization-level impact: 12, 1, 10, 13, 15
Personal interest: 4, 13, 11, 5, 15
Fewest teams attempting: 4, 13, 5, 11, 1, 15

How would you prioritise?

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